febrero 4, 2013 Fibrogel 0


Network for Development of Soft Nanofibrous Construct for Cellular Therapy of Degenerative Skeletal Disorders

The major objective of this project is to bring together the expertise of academia and industry partners for the development of an innovative complementary strategy for targeting bone and cartilage regeneration. They will be involved in the design of an advanced tissue engineering construct comprising of bioinspired gel with unique biomechanical properties containing oriented nanofibres and bioactive molecules resembling the natural spatiotemporal cues of the extracellular matrix. It is further combined with human mesenchymal stem cells (hMSC) differentiating into osteogenic or chondrogenic
lineages. This challenging approach requires collaboration of researchers from different disciplines such as materials science, chemistry, nanoengineering and cell biology. The involvement of both academia and industrial partners will assure the bidirectional transfer of knowledge and shall result in the creation
of commercial product(s) expecting medical application.

The proposed multidisciplinary approach aims to gain radical innovation in the strategy for treatment of the skeletal disorders with a strong impact in the long term for a variety of fields such as nanobioengineering and regenerative medicine.


Keywords: biomimetic gel, nanofibers, construct, hMSC, bone, cartilage


 Project details

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01-01-2013 to 31-12-2016

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Industry-Academia Partnerships and Pathways (IAPP)